If we have a rash on our face, we’re careful to treat the inflamed area until it disappears to prevent scarring. However, low-grade inflammation in the hypothalamic area (caused by the overconsumption of fats and carbohydrates), is hidden from our view. Inflammation in this area is a precursor for the development of metabolic and cognitive disorders (dementia) [38. This “hidden” inflammation is metabolic in nature and targets cells specialized in energy metabolism leading to insulin resistance .
If there’s just a short period (2-3 weeks) of consuming excess saturated fat and carbs in the diet, the effects of metabolic disturbance can be reversed. However, after a longer period, the neuroprotective mechanism fails resulting in inflammation . This inflammation leads to the production of cytokines and leads to deficiencies in insulin and leptin signaling . Reducing the intake of simple carbs, high fructose corn syrup, and saturated fats (inflammatory foods) helps our brain DETOX and recover from inflammation & immune system dysregulation .